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CIRCIT: Circit class therapy for Increasing Rehabilitation Intensity of Therapy trial

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CIRCIT: Circit class therapy for Increasing Rehabilitation Intensity of Therapy trial

CIRCIT is a multi-centre randomized controlled trial with assessor blinding. It is a 3-armed trial which aims to examine the effectiveness of two distinct models of increasing the dose of physiotherapy provided to people during sub-acute rehabilitation. Usual care physiotherapy (provided over 5 day week) is the control group and will be compared to usual care therapy provided over 7 days a week (7-day therapy) and group circuit therapy provided over 5-days a week (circuit class therapy). The group nature of circuit class therapy has been proven able to deliver an approximate four-fold increase in therapy dose per working day. The primary outcome is walking capacity (6 minute walk test) at 4 weeks. The secondary aim is to examine the relative cost-effectiveness of the dofferent models of care.

We are currently recruiting from three rehabilitation centres in South Australia, one in Western Australia amd a fifth site in Victoria soon to commence recruitment. Our target sample is 282.

Last Updated ( Wednesday, 10 January 2018 12:51 )

EXTEND: Extending the time for Thrombolysis in Emergency Neurological Deficits

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Phase III, randomised, multicentre, double blinded, placebo controlled trial (2 arm with 1:1 randomisation) within a larger cohort study of ischaemic stroke patients. Patients randomised to treatment will be stratified for time of randomisation after stroke to within <6 hours and 6-9 hours. The primary hypothesis being tested in this trial is that ischaemic stroke patients selected with significant penumbral mismatch (measured by MRI criteria) at 3 - 9 hours post onset of stroke will have improved clinical outcomes when given intravenous tissue plasminogen activator (tPA) compared to placebo.

A total of 400 participants shall be recruited.    

Extend Investigators in China

Last Updated ( Tuesday, 25 August 2015 13:14 )
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